Before the Pine Bluff Police Department standardized their duty weapons – you could pretty much carry anything you could qualify with and were willing to tote around on a duty belt for 8 plus hours a day. Good friend of mine carried a model 25 chambered in .45 Colt – I asked him W.T.A.F.? – he said “if I shoot have to somebody I want them to stay shot!” – Makes perfectly good sense to me . . .
And yes folks – they are available – quite a few listed on Gun Broker – or you should be able to order one from your local “Happy Happy Joy Joy” store – (Gun Shop for you uninitiated / unwashed masses – LOL! ) NOT a cheap date by any stretch – Ammo prices? – started reloading just to keep myself in practice rounds for my cowboy guns chambered for .45 Colt – there are quite a variety of “self defense” types of rounds available – but really folks – if a 255 grain lead flat point rumbling down the line at about 850 fps WON’T do it I really don’t know what to tell you except possibly call in artillery or an air strike – just saying . . .
And if YOU can’t decide between the Model 25 or a more “traditional “cowboy” gun? – buy them both – and you can tell your wife Bruce said it was OK – LMAO!
I even have a “conceal carry” cowboy type snub nose device chambered in .45 Colt – and it is one of the funnest guns that I have to go out and run a hundred or so rounds through that I own . . .

Barrel less than 4 inches make it a snubby – right?
The .45 Colt round is an absolute hoot to shoot – just something about that big old round lumbering along that just appeals to ME as much as a 230 grain .45acp does . . .
Have Fun! – Run the Gun! – and remember – Fish Heads are Cheap!!